There's nothing in principle that prevents other mechanisms from inducing the prion conditions that eventually leads to Alzheimer's symptoms. This paper is jus

There's nothing in principle that prevents other mechanisms from inducing the prion conditions that eventually leads to Alzheimer's symptoms. This paper is just another piece of evidence that points to the plaques and tangles being self propagating, instead of being say for example a pure by-product of some other mechanism. In itself, that doesn't really tell us anything about the mechanisms at play. Is it a game changer? Probably not. It's unlikely that Alzheimer's is purely spread through inter-human prion transmission, so other factors are likely still at play.