I've did a bit of experimentation with hexagonal layouts in the past, just for fun (hexagonal grids have some useful properties). But is has some problems that

I've did a bit of experimentation with hexagonal layouts in the past, just for fun (hexagonal grids have some useful properties). But is has some problems that make it very unconvenient to use: for example, you can't subdivide a hexagon into smaller hexagons. This makes for really wasteful layouts :)