2 ms·
Bingo. That would be really interesting. And useful. There are probably already enzymes in this data set that have measurements of their behavior. Could this m
by inciampati 8y ago
Bingo. That would be really interesting. And useful.
There are probably already enzymes in this data set that have measurements of their behavior. Could this modelling approach be coaxed to find the one with the highest processivity? Or do we need more labeled data?
- shpongled 8y agoI'm sure they have a bunch of enzymes in their dataset for which kinetic measurements have been published. Another interesting follow up study would attempting to improve kinetic behavior. They could, for instance, analyze some of the catalytically perfect enzymes out there (TIM, SOD, catalase, etc) and see if the model could project improvements onto existing orthogonal protein classes.
- jerven 7y agoNot in a structured way that is easily useable. Swiss-Prot has most of this data but it is not quite normalized in units. If you did this annoying work I would like to talk to you so we can plug it into Swiss-Prot.