Django works great if you're buying into the Django ecosystem. But if you're standing up a simple REST API, I've found Flask is much more flexible. Either appro

Django works great if you're buying into the Django ecosystem. But if you're standing up a simple REST API, I've found Flask is much more flexible. Either approach will get you to where you're going, but I find Flask gets out of your way and lets you do your thing, while you have to find the Django Way of doing what you need to do. This may be biased (I've been a Flask user since 0.7), and perhaps I'm stuck in my ways, but I've found I either need to find a supported and blessed Django plugin for the thing I need, or build something much more complex than I'd need in Flask.