I don't have a dog in this fight, but I did run into this (which doesn't answer the question, but is interesting) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC

I don't have a dog in this fight, but I did run into this (which doesn't answer the question, but is interesting) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622783/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622783/