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Congratulations on your progress! Interested why you decided against metformin. Lots of people without DM or Metabolic syndrome are taking it for its apparent
by et2o 7y ago
Congratulations on your progress!
Interested why you decided against metformin. Lots of people without DM or Metabolic syndrome are taking it for its apparent life extension effects (mostly unproven this far in humans). For diabetes, there's pretty solid evidence.
I work in this space tangentially and I had not heard of berberine before. What are you hoping to achieve with this supplement?
- cik2e 7y agoBerberine has been shown to be as effective as metformin at controlling blood sugar with additional anti-depressive benefits. https://examine.com/supplements/berberine/ https://examine.com/supplements/berberine/
- et2o 7y agoI don't think it's comparable. That link overstates the amount of evidence. Notably the only good trial didn't compare it to metformin. Three small trials and a meta analysis. There is decades of experience with and significant evidence for the efficacy of metformin.
- atomical 7y agoMetformin is great if you like shitting your pants constantly. The life extension crowd is going to give us a lot of laughs.
- LinuxBender 7y agoBerberine can do that as well. You have to start off with small doses and let things adjust. I've been doing so many supplements for so long that it didn't really affect me much.