I don't know about Guile's popularity, but I use NixOS as my daily driver distro and in my experience Nix is already very niche in the programming circles I run

I don't know about Guile's popularity, but I use NixOS as my daily driver distro and in my experience Nix is already very niche in the programming circles I run in. That's not to say Guix shouldn't be developed or that Shepherd is bad, it's just that I would definitely call Guix niche.