PyQt all the way! Both for my hired gun projects (WengoPhone, QuteCom) and for my personal projects. The UI toolkit (QtGui) is great: the widgets have a native

PyQt all the way! Both for my hired gun projects (WengoPhone, QuteCom) and for my personal projects. The UI toolkit (QtGui) is great: the widgets have a native look and feel on all platforms (deal breaker otherwise for me), you have an good UI designer etc. But Qt has more libs! File parsers, a signal/slot library for asynchronous calls (which you pretty much have to use with QtGui).