2 ms·
Restoration of brain circulation and cellular functions hours post-mortem
- kensai 8y agoWell, last sentence is obviously critical. Although impressive, a healthy EEG/ECoG signal means all the world for practical purposes. "We have developed an extracorporeal pulsatile-perfusion system and a haemoglobin-based, acellular, non-coagulative, echogenic, and cytoprotective perfusate that promotes recovery from anoxia, reduces reperfusion injury, prevents oedema, and metabolically supports the energy requirements of the brain. With this system, we observed preservation of cytoarchitecture; attenuation of cell death; and restoration of vascular dilatory and glial inflammatory responses, spontaneous synaptic activity, and active cerebral metabolism in the absence of global electrocorticographic activity."