The "micro level" is almost completely irrelevant. Performance comes from doing the right thing globally, and it will be a long time before tools can help there

The "micro level" is almost completely irrelevant. Performance comes from doing the right thing globally, and it will be a long time before tools can help there. I conjecture that apart from a few artificial benchmarks, the choice of the different approaches here is totally irrelevant. Just don't use the 10000ms approach, and you won't notice a difference in 99% of the real world applications.