2 ms·
What am I missing here? Rodent studies routinely use whole brain and slice tissues for long term neuro-experimentation [0]. You can keep slices alive for days
by Balgair 8y ago
What am I missing here?
Rodent studies routinely use whole brain and slice tissues for long term neuro-experimentation [0]. You can keep slices alive for days on end, if you're careful [1]. Is it just that it's a whole pig brain that they used these tried and true techniques with? Ischemia isn't something to laugh at, it's very tough to deal with. But the 'ethical' issues have long been put to bed, we've been doing this since 1951 [2]
[0] https://www.ncbi.nlm.nih.gov/pubmed/28744893 https://www.ncbi.nlm.nih.gov/pubmed/28744893
[1] https://www.ncbi.nlm.nih.gov/pubmed/9914290 https://www.ncbi.nlm.nih.gov/pubmed/9914290
[2] McIlwain, H., Buchel, L. & Cheshire, J. D. The inorganic phosphate and phosphocreatine of Brain especially during metabolism in vitro. Biochem. J. 48, 12–20 (1951).