I'm sure there are better ways to do this, but if you really want Python client code -> WASM -> Python host, I'd imagine you could probably run https://github.c

I'm sure there are better ways to do this, but if you really want Python client code -> WASM -> Python host, I'd imagine you could probably run https://github.com/iodide-project/pyodide https://github.com/iodide-project/pyodide within Wasmer. But you'd likely lose a lot of the performance benefits of numpy etc. being compiled for the exact intrinsics supported by your host CPU. Container-level sandboxing still sounds like a superior bet.