To add another n=1, I have severe allergies, not quite life threatening but almost (partial but significant throat constriction upon exposure), and I've never h

To add another n=1, I have severe allergies, not quite life threatening but almost (partial but significant throat constriction upon exposure), and I've never had a cavity and seem almost incapable of getting one. I only brush one time, at night, and don't use toothpaste (couldn't find one I wasn't mildly sensitive to). It is established that immune cells are modulated by microbiota - and yes, there are oral microbiota, and there are even oral probiotic supplements one can take which seem to be effective for certain conditions. If you are interested in this topic, I'd recommend paying close attention to how the 2 main strains were discovered (S. Salivarius K12 and M18) - iirc. at least one of the two was first extracted from a child who had no cavities.