3 ms·
The short answer is that no one knows. It's likely we won't know for a long time. As for this study, a side-effect of naltrexone is depression. That would seem
by atomical 7y ago
The short answer is that no one knows. It's likely we won't know for a long time.
As for this study, a side-effect of naltrexone is depression. That would seem to me to make it unsuitable to use in a study with ketamine.
Relevant:
Caution Against Overinterpreting Opiate Receptor Stimulation as Mediating Antidepressant Effects of Ketamine
https://www.ncbi.nlm.nih.gov/pubmed/30818991 https://www.ncbi.nlm.nih.gov/pubmed/30818991
https://sci-hub.tw/10.1176/appi.ajp.2018.18091061r https://sci-hub.tw/10.1176/appi.ajp.2018.18091061r