During the Depression, there was discrimination against internal migrants, famously the "Okies" moving from Oklahoma to western states. They were the subject of

During the Depression, there was discrimination against internal migrants, famously the "Okies" moving from Oklahoma to western states. They were the subject of all kinds of negative stereotypes, and were sometimes turned away at the border or put into labor camps. I don't think serious discrimination on the scale described in the article has recently happened to US citizens in the continental US, however.