Note that absorption and metabolization rates can affect the safety profile; for example, this is why acetaminophen is generally safe at lower doses, but quickl

Note that absorption and metabolization rates can affect the safety profile; for example, this is why acetaminophen is generally safe at lower doses, but quickly becomes hepatotoxic at higher doses, because different metabolic pathways come into play: https://en.m.wikipedia.org/wiki/Paracetamol_poisoning#Pathophysiology https://en.m.wikipedia.org/wiki/Paracetamol_poisoning#Pathop...