4 ms·
> For older people higher LDL is actually protective, for women there seems to be nearly no effect whatsoever. Don't be fooled by simple answers. Your last sta
by spraak 8y ago
> For older people higher LDL is actually protective, for women there seems to be nearly no effect whatsoever. Don't be fooled by simple answers.
Your last statement is in direct contradiction with all of your previous simple answers. Where is there evidence of the protective effect of LDL?
- JanSt 8y agoHow so? LDL can be a marker of bad health, but is not so by any means in all cases. Relevant study: https://bmjopen.bmj.com/content/6/6/e010401 https://bmjopen.bmj.com/content/6/6/e010401
- spraak 8y agoThat study is problematic: https://www.cebm.net/2016/06/cebm-response-lack-association-inverse-association-low-density-lipoprotein-cholesterol-mortality-elderly-systematic-review-post-publication-pee/ https://www.cebm.net/2016/06/cebm-response-lack-association-... And just one? Lots of studies showing the opposite.
- JanSt 8y agoI'm not here to dig up all studies showing those results. Here is (probably the best) one. The MCE was orignally designed to show the opposite: https://www.bmj.com/content/353/bmj.i1246 https://www.bmj.com/content/353/bmj.i1246
- JanSt 8y agoBtw, it's not "just one" study, but a meta study. I guess you understand the difference? Please link the studies showing the opposite results.
- rhinoceraptor 8y agoLike pretty much everything, there's a U shaped curve. Low cholesterol can be bad, just as high cholesterol can be bad. Plus, it could just be a side effect of something else and we don't actually know what the underlying cause is.