Quality of the PCB and the number of layers definitely plays a factor I'm sure it isn't limited to ITX though. I have noticed compatible differences between sup

Quality of the PCB and the number of layers definitely plays a factor I'm sure it isn't limited to ITX though. I have noticed compatible differences between super robust Intel ITX boards vs ECS thin and wobbly ITX boards, with the ECS board having more issues, quirks and what not.