IMO the physical separation of multiple monitors helps with cognitive load. Work GREAT when you need to look at some kind of references often. You don't need to

IMO the physical separation of multiple monitors helps with cognitive load. Work GREAT when you need to look at some kind of references often. You don't need to think about window switching at all, you just know what you need is there, ready for you to glance at anytime. Also work great with program that consists of multiple panels e.g. After Effects/Premiere Pro. You can do that with one big screen and a good window manager, but the effect may not be the same. One extra monitor is good enough for most people, but to each his own. The downside is of course, it's not the most minimal setup. But when you're in the zone, you don't care about the aesthetic anyway.