Note that it MUST be taken prior to consumption: "Pretreatment with NAC significantly protected against acute ethanol-induced liver damage in a dose-independen

Note that it MUST be taken prior to consumption: "Pretreatment with NAC significantly protected against acute ethanol-induced liver damage in a dose-independent manner. Correspondingly, pretreatment with NAC significantly attenuated acute ethanol-induced lipid peroxidation and GSH depletion and inhibited hepatic TNF-alpha mRNA expression. By contrast, post-treatment with NAC aggravated ethanol-induced hepatic lipid peroxidation and worsened acute ethanol-induced liver damage in a dose-dependent manner. Taken together, NAC has a dual effect on acute ethanol-induced liver damage. Pretreatment with NAC prevent from acute ethanol-induced liver damage via counteracting ethanol-induced oxidative stress. When administered after ethanol, NAC might behave as a pro-oxidant and aggravate acute ethanol-induced liver damage." https://www.ncbi.nlm.nih.gov/pubmed/16439183 https://www.ncbi.nlm.nih.gov/pubmed/16439183