First thing, don't panic. (And I'm not trying to play on HHGTTG...). So don't go rush out and liquidate all of your investments. Second, always make sure you

First thing, don't panic. (And I'm not trying to play on HHGTTG...). So don't go rush out and liquidate all of your investments. Second, always make sure you personally have a plan with savings for at least 6 months or more. Think about what would you do tomorrow if your source of income stopped and you had to make it for a year without any more income. How would your life style change? What sacrifices would you have to make? Unfortunately, many people have very little to no savings and this isn't even an option. If you are close to retiring (5-10 years or less), consult a financial advisor who you trust. At this point, you should have enough to live off of in safe/less volatile investments. As a startup founder, I think the macro economics side is the last of your worries on a long list... you should always have contingencies for things not going right. For instance, a large company releases a competing product to you tomorrow...