25i-nbome is a popular ligand for 5-ht2a activation due to its high potency (low amount required for action), stability, and iodine content (can be made radioac

25i-nbome is a popular ligand for 5-ht2a activation due to its high potency (low amount required for action), stability, and iodine content (can be made radioactive without altering the structure). Someone probably had a thought about 5-ht2a stimulation leading to neurogenesis and tested it in mice using 25i because it's a good compound for that. Thus the headline "25i-nbome causes brain cell growth". (The psychedelic action of 5-ht2a ligands may have been a clue that they cause neurogenesis. Until tested it's only a guess.)