5 ms·

I thought nerves aren't regenerated either?

wickedsmile 8y ago
Intact I read somewhere Cannabis consumption results in Neurogenesis. I am trying to find something for citation but unable to find anything backing this claim
- darkpuma 8y ago
  Cannabis's Schedule I status makes it difficult for legitimate researchers to debunk (or confirm) the ever growing volume of nonsense cannabis proponents put forward to support legalization. Which ironically, is a pretty good argument for rescheduling it at least.
- meko 8y ago
  Claims of legitimacy aside, The CBD portion of cannabis is supposed to have this affect, not thc.
  - heavenlyblue 8y ago
    Why CBD specifically? Where do you get that data?
magduf 8y ago
They certainly do. From a very quick google search: https://www.sciencedaily.com/releases/2010/09/100927141144.htm https://www.sciencedaily.com/releases/2010/09/100927141144.h...
ergothus 8y ago
It was thought so for a while, but recently (~10-20 years) was discovered that they do, albeit slowly.
adrianmonk 8y ago
They are sometimes. One of mine did. I had some nerve damage a while back and went to a neurologist. He did an EMG test (https://en.wikipedia.org/wiki/Electromyography https://en.wikipedia.org/wiki/Electromyography) and confirmed the nerve was damaged. He used electrodes to show that it did not conduct electricity like it was supposed to, nor did it conduct electricity like the corresponding one on the other side of my body. (Somewhere, I have a printout showing voltage and latency numbers.) He then told me that if the damage is not too great, nerves can repair themselves, that the repair proceeds outward from the brain toward the periphery of the body, and that it happens at a rate of roughly 1 millimeter per day. So, he said, my problem would probably resolve itself but it would be a long time, think 6 months or a year, maybe even longer to finally be back to 100%. And it basically happened just like he said it would. 6 months later, it was a lot better, and it continued to gradually improve from there. He also mentioned that using the affected muscles would help encourage healing. I think he meant the nerve itself would heal faster this way, not just that it would help reverse muscle atrophy.
- holoduke 8y ago
  So instead of growing back the missing /damaged nerve, an entire new nerve string grew from the brains back to the original nerve? Didn't know that
  - adrianmonk 8y ago
    My layman's understanding is that a nerve is kind of a bundle of fibers wrapped in an outer layer. (Perhaps it's reasonable to compare it to a stranded wire inside an insulator, though I wouldn't say for sure.) He said that if the outer layer is intact, the inner layer can be repaired. I'm not sure if that means more nerve fibers form or that existing nerve fibers are repaired but that the repair takes place incrementally instead of all at once. Intuitively it seems to make sense that a new fiber is growing, but I'm wary of speculating based on what seems to make sense to me.
redcalx 8y ago
I cut a nerve at the base of my middle finger one time and completely lost feeling. Feeling came back over two or three weeks as the cut healed and eventually came back 100%.
m00x 8y ago
Peripheral nerves are well known to regenerate, but the spinal nerves do not (or very limited). We do not want nerves to regenerate in most cases because it could cause even worse results. If you start regrowing a batch of nerve, you have a chance of growing out nerves that transfer pain signals into places you don't want them to be, which could cause persistent neuropathic pain (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290455/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290455/).

Intact I read somewhere Cannabis consumption results in Neurogenesis. I am trying to find something for citation but unable to find anything backing this claim

darkpuma 8y ago
Cannabis's Schedule I status makes it difficult for legitimate researchers to debunk (or confirm) the ever growing volume of nonsense cannabis proponents put forward to support legalization. Which ironically, is a pretty good argument for rescheduling it at least.
meko 8y ago
Claims of legitimacy aside, The CBD portion of cannabis is supposed to have this affect, not thc.
- heavenlyblue 8y ago
  Why CBD specifically? Where do you get that data?

magduf 8y ago

They certainly do. From a very quick google search: https://www.sciencedaily.com/releases/2010/09/100927141144.htm https://www.sciencedaily.com/releases/2010/09/100927141144.h...

ergothus 8y ago

It was thought so for a while, but recently (~10-20 years) was discovered that they do, albeit slowly.

adrianmonk 8y ago

They are sometimes. One of mine did. I had some nerve damage a while back and went to a neurologist. He did an EMG test (https://en.wikipedia.org/wiki/Electromyography https://en.wikipedia.org/wiki/Electromyography) and confirmed the nerve was damaged. He used electrodes to show that it did not conduct electricity like it was supposed to, nor did it conduct electricity like the corresponding one on the other side of my body. (Somewhere, I have a printout showing voltage and latency numbers.) He then told me that if the damage is not too great, nerves can repair themselves, that the repair proceeds outward from the brain toward the periphery of the body, and that it happens at a rate of roughly 1 millimeter per day. So, he said, my problem would probably resolve itself but it would be a long time, think 6 months or a year, maybe even longer to finally be back to 100%. And it basically happened just like he said it would. 6 months later, it was a lot better, and it continued to gradually improve from there. He also mentioned that using the affected muscles would help encourage healing. I think he meant the nerve itself would heal faster this way, not just that it would help reverse muscle atrophy.

holoduke 8y ago
So instead of growing back the missing /damaged nerve, an entire new nerve string grew from the brains back to the original nerve? Didn't know that
- adrianmonk 8y ago
  My layman's understanding is that a nerve is kind of a bundle of fibers wrapped in an outer layer. (Perhaps it's reasonable to compare it to a stranded wire inside an insulator, though I wouldn't say for sure.) He said that if the outer layer is intact, the inner layer can be repaired. I'm not sure if that means more nerve fibers form or that existing nerve fibers are repaired but that the repair takes place incrementally instead of all at once. Intuitively it seems to make sense that a new fiber is growing, but I'm wary of speculating based on what seems to make sense to me.

redcalx 8y ago

I cut a nerve at the base of my middle finger one time and completely lost feeling. Feeling came back over two or three weeks as the cut healed and eventually came back 100%.

m00x 8y ago

Peripheral nerves are well known to regenerate, but the spinal nerves do not (or very limited). We do not want nerves to regenerate in most cases because it could cause even worse results. If you start regrowing a batch of nerve, you have a chance of growing out nerves that transfer pain signals into places you don't want them to be, which could cause persistent neuropathic pain (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290455/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290455/).