> The trouble is all the hypotheses are lies The problem with p values is the opposite: in a complex system, null hypothesis is almost never true. Everything a

> The trouble is all the hypotheses are lies The problem with p values is the opposite: in a complex system, null hypothesis is almost never true. Everything affects everything else. It's the magnitude of the effect that is important, because it can be too small to have practical implications. If you do enough studies eventually you'll find a result with p value below 0.05 that will overestimate the magnitude of the effect by a lot, and publish it.