4 ms·
Esketamine doesn’t have the same activity as racemic or Arketamine (S- hits some of the dopamine receptors harder and doesn’t bind with the sigma ones iirc). Pa
by mveety 8y ago
Esketamine doesn’t have the same activity as racemic or Arketamine (S- hits some of the dopamine receptors harder and doesn’t bind with the sigma ones iirc). Patients seem to find esketamine more pleasant because of this and it’s eliminated faster than R- so patients can (probably) get back to normal faster.
(Edit: had my right from left mixed up. It’s been a while)
- dawhizkid 8y agoSo maybe it makes you a little less groggy but at 300x the price? Don't think anyone can say that justifies the price multiple.
- xkcd-sucks 8y agoNow r-ket can be developed as a patentable improvement over the state of the art :)