3 ms·

No[0], it won't [1], that's the point of the article. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870486 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC487

No[0], it won't [1], that's the point of the article. [0] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870486 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870486 [1] https://academic.oup.com/jn/article-abstract/125/11/2891S/4730581?redirectedFrom=fulltext https://academic.oup.com/jn/article-abstract/125/11/2891S/47...

kazinator 8y ago
[0] is shill work by researchers working for a MSG manufacturer. I have seen this before. One even has an "ajiusa.com" e-mail address right there, /palmface/. Can't comment on on [1]: the entire paper is paywalled as far as I can see, not even a hint at the results. Let's try something else: Graham TE, Sgro V, Friars D, Gibala MJ. 2000. Glutamate ingestion: the plasma and muscle free amino acid pools of resting humans. American Journal of Physiology-Endocrinology and Metabolism 278:E83–89. These researchers provided single 150mg/kg oral doses of MSG to 9 healthy volunteers (8 males, 1 female) to determine the plasma and muscle concentrations of glutamate following ingestion. All volunteers reported transient headaches. Shimada A, Cairns BE, Vad N, Ulriksen K, Pedersen AML, Svensson P, Baad-Hansen L. 2013. Headache and mechanical sensitization of human pericranial muscles after repeated intake of monosodium glutamate (MSG). Journal of Headache and Pain 14:2 More than 50% of healthy, male subjects given 150mg/kg daily doses developed headaches.
- loeg 8y ago
  > Let's try something else N=8 or 9 (low power), 150 mg/kg(!) doses. That's like ingesting 11 g of the stuff for a 75 kg adult.
drewmol 8y ago
from [0]: >Because of the absence of proper blinding, and the inconsistency of the findings, we conclude that further studies are required to evaluate whether or not a causal relationship exists between MSG ingestion and headache.
- kazinator 8y ago
  And that's from people paid by their boss to show that there is no such effect.

kazinator 8y ago

[0] is shill work by researchers working for a MSG manufacturer. I have seen this before. One even has an "ajiusa.com" e-mail address right there, /palmface/. Can't comment on on [1]: the entire paper is paywalled as far as I can see, not even a hint at the results. Let's try something else: Graham TE, Sgro V, Friars D, Gibala MJ. 2000. Glutamate ingestion: the plasma and muscle free amino acid pools of resting humans. American Journal of Physiology-Endocrinology and Metabolism 278:E83–89. These researchers provided single 150mg/kg oral doses of MSG to 9 healthy volunteers (8 males, 1 female) to determine the plasma and muscle concentrations of glutamate following ingestion. All volunteers reported transient headaches. Shimada A, Cairns BE, Vad N, Ulriksen K, Pedersen AML, Svensson P, Baad-Hansen L. 2013. Headache and mechanical sensitization of human pericranial muscles after repeated intake of monosodium glutamate (MSG). Journal of Headache and Pain 14:2 More than 50% of healthy, male subjects given 150mg/kg daily doses developed headaches.

loeg 8y ago
> Let's try something else N=8 or 9 (low power), 150 mg/kg(!) doses. That's like ingesting 11 g of the stuff for a 75 kg adult.

drewmol 8y ago

from [0]: >Because of the absence of proper blinding, and the inconsistency of the findings, we conclude that further studies are required to evaluate whether or not a causal relationship exists between MSG ingestion and headache.

kazinator 8y ago
And that's from people paid by their boss to show that there is no such effect.