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Chronic High Cholesterol Diet Produces Brain Damage

• Udo 16y ago
  ...in mice, at least. It is well-documented that high-fat, high-cholesterol diets cause damage to the arterial lining due to inflammatory processes when fatty macromolecules attach to the walls of blood vessels and cannot be removed by the immune system (cellular debris from the immune reaction to this is what constitutes arterial plaques). I think it's logical that brain tissue also suffers through that mechanism, causing local ischemic micro-episodes and possibly the migration of inflammation signals into the brain tissue, both of which cannot be good for neurons.