That can happen. But in a significant (the majority?) number of cases of patients diagnosed with Schizophrenia there is no difference between their brains and '

That can happen. But in a significant (the majority?) number of cases of patients diagnosed with Schizophrenia there is no difference between their brains and 'normal' people when comparing MRI scans. Note this is with early onset - the "medication" provided for schizophrenia is well known to cause large structural changes in the brain.