Some people are working on optimizing ruby "bytecode" (what the VM interprets): https://developers.redhat.com/blog/2019/02/19/register-transfer-language-for-cru

Some people are working on optimizing ruby "bytecode" (what the VM interprets): https://developers.redhat.com/blog/2019/02/19/register-transfer-language-for-cruby https://developers.redhat.com/blog/2019/02/19/register-trans... I'm pretty sure the same concepts could be applied to CPython.