2 ms·
> does tend to cluster in families. Yes but not necessarily at the sibling level, which is what you'd expect if this was a problem caused by bad mothers. Also
by ericb 8y ago
> does tend to cluster in families.
Yes but not necessarily at the sibling level, which is what you'd expect if this was a problem caused by bad mothers.
Also, you would predict that siblings should be highly correlated regardless of their genes if it was "mothering" but instead what you find is this (from the study you cited):
Monozygotic Twins 44.3
Offspring two schizophrenic parents 36.6
Dizygotic Twins 12.1
Siblings 7.3
Offspring one schizophrenic parent 9.4
Half-siblings 2.9
So a half-sibling raised with the same parenting is barely correlated on schizophrenia, but a twin has a 44 percent correlation. That puts the schizophrenogenic mother theory 100% off the reservation in my book. Reasoning past that damning fact is just wishful thinking.
> I don't see how this theory conflicts with whatever
The average age of onset is 18 in men and 25 in women. If this disordered thinking style is created in say 6 year olds, it seems odd that it takes 12-20 years to cause a problem.
Anyhow theories are a dime a dozen, and the burden of proof is on those proposing the theory to prove it, and that has failed rather spectacularly in this case.
https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-15877-8_482-1 https://link.springer.com/referenceworkentry/10.1007%2F978-3...
https://journalofethics.ama-assn.org/article/ghost-schizophrenogenic-mother/2013-09 https://journalofethics.ama-assn.org/article/ghost-schizophr...
https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-15877-8_482-1 https://link.springer.com/referenceworkentry/10.1007%2F978-3...
Separated twins show high concordance for schizophrenia (why would this be if it is due to parenting?)
https://www.ncbi.nlm.nih.gov/pubmed/2285075 https://www.ncbi.nlm.nih.gov/pubmed/2285075
Another study:
https://journals.sagepub.com/doi/pdf/10.1177/1403494810396560 https://journals.sagepub.com/doi/pdf/10.1177/140349481039656...
The important bit: It was concluded that genetic factors are important in the transmission of schizophrenia, whereas there was no evidence for environmental influences in the rearing family.