To be clear though, This was a nuts concept until Yamanaka blew everyone's minds. When I read cell biology texts in 2008 the "dogma" was that differentiation w

To be clear though, This was a nuts concept until Yamanaka blew everyone's minds. When I read cell biology texts in 2008 the "dogma" was that differentiation was a one way route. I've had the pleasure of attending classes by a prominent stem cell person who presided over the conference session where Yamanaka presented his findings first. Apparently everyone just thought he was nuts. People only believed it when the original cell paper came out. Definitely one of my favorite biology papers of all time!