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That's not necessarily true. For example, humans do not have Neu5Gc[1] unlike most mammals. Having Neu5Gc antibodies is perfectly compatible with human life, ye
by druidcz 8y ago
That's not necessarily true. For example, humans do not have Neu5Gc[1] unlike most mammals. Having Neu5Gc antibodies is perfectly compatible with human life, yet consumption of lamb, pork or beef can cause inflammation.
[1] https://en.wikipedia.org/wiki/N-Glycolylneuraminic_acid https://en.wikipedia.org/wiki/N-Glycolylneuraminic_acid
- TheSpiceIsLife 8y agoThanks for bringing this up, I wasn't aware of it.
- virtuallynathan 8y agoAFAIK, none of these studies have been done on humans.
- druidcz 8y agoThe popular article where I read about it referenced: [1] [2]. I guess it is a quite recent finding. But I am no biologist to judge. [1] Okerblom J., Varki A.: Biochemical, Cellular, Physiological, and Pathological Consequences of Human Loss of N-Glycolylneuraminic Acid, ChemBioChem 18, 1155, 2017, DOI: 10.1002/cbic.201700077 [2] Peri S. et al.: Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc, Genome Biology and Evolution, 2018, DOI: 10.1093/gbe/evx251