3 ms·
It might be a realy big milestone if it comes to market. Especially if it could come out as soon as within this year. Sometimes I hear people mention that keta
by pizza 8y ago
It might be a realy big milestone if it comes to market. Especially if it could come out as soon as within this year.
Sometimes I hear people mention that ketamine’s special effectiveness (in those whom it is effective, which isn’t 100% of people afaik) wears off over the length of a treatment protocol. It’d be nice to hear more about that, especially in comparison to the long-term effectiveness of traditional antidepressants and SSRIs in particular.
- indalo 8y agoThis. I've read some horror stories about patients that received infusions which for a time, gave them their life back, and suddenly for all intents and purposes it became ineffective. Some people described going back to feeling depressed after seeing the alternative to be even less bearable. I'm eager to see it come to market, and for it to work, but I'm scared to work with my doctor to try it based on those stories.
- rincebrain 8y agoCan confirm that this happens. To put it mildly, not the most pleasant experience of my life, but still looking forward to seeing where the next iterations on rapid-acting antidepressants go, and whether they turn out to be any more durable. (Also quite curious to see what research crops up about why the effects are sometimes not durable, but that's gonna be a decent wait.)
- 0xcde4c3db 8y agoAs far as I've read, ketamine trials have mostly focused on patients for whom traditional treatments haven't worked or haven't had a sustained effect ("treatment-resistant depression" or "treatment-refractory depression"). So I doubt that this is being positioned as something that would attempt to replace traditional treatments.