This doesn't sound right. The Wikipedia entry for fructose[1] has this to say: Excessive consumption of fructose may contribute to insulin resistance, obesity

This doesn't sound right. The Wikipedia entry for fructose[1] has this to say: Excessive consumption of fructose may contribute to insulin resistance, obesity, elevated LDL cholesterol and triglycerides, leading to metabolic syndrome, type 2 diabetes and cardiovascular disease. So it would appear fructose does cause an insulin response. However, it then goes on to say: Uptake of fructose by the liver is not regulated by insulin. However, insulin is capable of increasing the abundance and functional activity of GLUT5 in skeletal muscle cells. (emphasis mine) GLUT5 is also expressed in skeletal muscle,testis, kidney, fat tissue (adipocytes), and brain.[2] 1. https://en.wikipedia.org/wiki/Fructose https://en.wikipedia.org/wiki/Fructose 2. https://en.wikipedia.org/wiki/GLUT5 https://en.wikipedia.org/wiki/GLUT5