I'll echo the same from other commentators. There are a LOT of issues with reproducbility in Bio [0] at the moment, and in US based science in general. From ot

I'll echo the same from other commentators. There are a LOT of issues with reproducbility in Bio [0] at the moment, and in US based science in general. From others in 'Big Pharma' that I know, they agree that much of bio-tech based science needs to be re-run. Others in the comments section here point out that Mainland China has a history of suspect research. That may have been true 5 years ago, but they are 'up to par' with US based researchers now. Meaning, that the Chinese have gotten more rigorous and the US has severely slipped in quality. I mean this next statement with full honestly: I don't believe half the labs out there in the US these since about 2016 onward. From very private conversations with others, many labs are abusive, fraudulent, 'me-too' landmines, and generally lying to grant funders, donors, and potential/enrolled students in a strange game akin to 'Catch Me If You Can' style con-artistry. Major efforts are being taken to 'fix' the system. Me-Too is a perfect example. The Nature paper that is linked is another perfect example. These efforts are very much needed and those that undertake these efforts should be applauded and emulated. That said, Max Planck's quote is the speed at which this change will occur, namely, one funeral at a time[2]. [0] https://www.reuters.com/article/us-science-cancer-idUSBRE82R12P20120328 https://www.reuters.com/article/us-science-cancer-idUSBRE82R... A bit old, but should get you started on more up-to-date research. [1] https://www.theatlantic.com/health/archive/2018/09/what-is-food-science/571105/ https://www.theatlantic.com/health/archive/2018/09/what-is-f... Food Science, but it illustrates the structure that leads to fraud. [2] https://en.wikiquote.org/wiki/Max_Planck https://en.wikiquote.org/wiki/Max_Planck