I think it's not just sugar. We want to single out a single culprit, but it's a multi-faceted problem. We are adapted to digest glucose and fructose, it could t

I think it's not just sugar. We want to single out a single culprit, but it's a multi-faceted problem. We are adapted to digest glucose and fructose, it could trace toxins in the process of making it, it could be a combination of lifestyle plus tons of fructose, it could be the disrupted circadian rhythm - nobody really knows. For sure, we've never had so much vegetable fat. According to Ray Peat, more than a gram of polyunsaturated fat is toxic and cancer-causing. According to a few of his followers, the desaturation of cardiolipin in mitochondria leads to instability and mitochondrial dysfunction, which is now recognized as the cause of many chronic diseases. I read that the iron overload, which replaces manganese with iron in the mitochondria is another possible culprit. Honestly, I have the gut feeling glucose is totally fine - even in large quantities. And Ray Peat thinks the same.