I use two 28 inch 4K monitors side by side with Linux on my workstation, and there is a bit of that issue. I ended up cranking up the acceleration on my pointe

I use two 28 inch 4K monitors side by side with Linux on my workstation, and there is a bit of that issue. I ended up cranking up the acceleration on my pointer input to easily toss the cursor around the whole desktop, and sometimes find myself annoyed with detail work or trying to drag very small targets and instead clicking something else nearby. Another issue is that after returning to the screen after some time, I can sometimes lose track of where the cursor is and have to thrash it around to cause enough motion for me to easily find it on the huge work area.