So there is no distinction between natural selection and human directed artificial selection? I thought the whole point of the term was whether humans where doi

So there is no distinction between natural selection and human directed artificial selection? I thought the whole point of the term was whether humans where doing the modification producing organisms that would not otherwise exist in nature. How humans accomplish the genetic modification seems to be the point of contention and I argue its poorly defined as there are many techniques in between selective breeding and gene insertion that we use to perform the modification.