Given that there's a WASM backend to LLVM, once WASM can be used without the need to interface with JS then any language with a WASM frontend (there'll probably

Given that there's a WASM backend to LLVM, once WASM can be used without the need to interface with JS then any language with a WASM frontend (there'll probably be the need for some basic library support) will become a viable replacement. At the moment however (I believe that it's still the case), WASM still needs to interact with the DOM via JS, so there's a minimum amount of JS boilerplate required for bootstrapping.