The issue is that we have an incredible dearth of knowledge about the effects of low gravity compared to either normal gravity or microgravity. If the ISS cent

The issue is that we have an incredible dearth of knowledge about the effects of low gravity compared to either normal gravity or microgravity. If the ISS centrifuge had actually flow the situation might be different but when considering settlement of either the Moon or Mars we desperately need more information about how low gravity affects biological systems. From the Apollo missions we do know that humans can survive for three days on the Moon, but given that humans can survive for months in orbit this isn't a surprise. But what are the effects on animal gestation? On plant growth? As far as I'm aware there weren't any plants on any of the Apollo missions, though I believe they did experiments with lunar regolith on Earth.