You cannot use Nix package definitions with Guix. You can, however, easily extend or modify Guix packages. New package definitions can inherit from existing o

You cannot use Nix package definitions with Guix. You can, however, easily extend or modify Guix packages. New package definitions can inherit from existing ones and override fields that you may want to change. There is also an API for rewriting dependencies recursively: https://www.gnu.org/software/guix/manual/en/html_node/Defining-Packages.html#index-dependency-tree-rewriting https://www.gnu.org/software/guix/manual/en/html_node/Defini... You can also use Nix as a package manager on top of a Guix system (and vice versa).