Highly directional EMP or something similar seems like it could work, if it existed and didn’t represent an insane proliferation and terrorism threat... which i

Highly directional EMP or something similar seems like it could work, if it existed and didn’t represent an insane proliferation and terrorism threat... which it would. Nor does it solve the problem of the drone falling out of the sky. Truth be told, nothing is going to reliably mitigate the drone or its wreckage crashing, so any interception should ignore the contribution of the drone itself to the safety environment. If a countermeasure is deployed, it’s going to present a risk to the public. That being the case, a SAM with a net warhead, some kind of rapidly setting foam, or a load of tangling wires seems like it would be most reliable without having to worry about UXO. You could even try to mitigate falling risk by ensuring the interceptor remains attached to the target, and then deploys a series of parachutes.