For me, the following is a lot more readable than cadadr: (def coll [[1 2 3] [4 5 6] [7 8 9]]) (second (second coll)) ; => 5 And

For me, the following is a lot more readable than cadadr: (def coll [[1 2 3] [4 5 6] [7 8 9]]) (second (second coll)) ; => 5 And often when I'm digging deep inside a nested data structure, I don't need just one piece of data, so destructuring comes in handy: (let [[[top-left] [_ middle] [_ _ bottom-right]] coll] [top-left middle bottom-right]) ; => [1 5 9]