Agreed re: target discovery. Most of the 23andMe data is not much better than what is already publicly available to researchers via initiatives like the UK Biob

Agreed re: target discovery. Most of the 23andMe data is not much better than what is already publicly available to researchers via initiatives like the UK Biobank. 23andMe uses the Illumina Global Screening array which has significantly worse output (in terms of number of SNPs) than the 500k patients genotyped in the UK Biobank. Furthermore these genotyping based assays make it impossible to detect rare variants that have never been seen before and may be protective. The data being generated by Helix is probably much better for target discovery, but still not competitive with private datasets constructed by companies like Regeneron.