I think there are some simple situations that provoke this type of response. The first is that while there are protections in place they are only paper protecti

I think there are some simple situations that provoke this type of response. The first is that while there are protections in place they are only paper protections. History has shown us those are not always effective. What if 23andme goes bankrupt and the data is "lost" or just sold to the lowest bidder? I am not certain of the legal loopholes present, but I wouldn't doubt we'll see a case of this happening in the next decade. The second is long term exposure to the unknown. Even if you knowingly choose to opt-in, what if that data is used against said persons at some point in the future for something they failed to consider, maybe because they couldn't know because it's not been identified as of yet? Profit isn't always the detractor. I get that these organizations need to make money. But without proper explanation (there should be a better legal framework in place for services like this that offer equal protections to both sides) and a potentially biased legal agreement, informed users will likely question the unknown of giving up information to a company who will continually be realizing ways to use your DNA for the foreseeable future. And, oh by the way, you paid them to do that. $0.02