Backend : Since I am more comfortable writing python, for speed and perf i would go for Sanic, it's pretty similar to Flask with async function. For personal or

Backend : Since I am more comfortable writing python, for speed and perf i would go for Sanic, it's pretty similar to Flask with async function. For personal or MVP I would use Flask with Peewee or Django depending on the complexity. Frontend : React for dynamic page only if i really need it. The rest would simply use any jinja provided by the backend framework. Database : small project sqlite ( personal blog, MVP ), postgresql for production level. For extremely fast and simple RESTful setup I would go for loopbackwhich has nice cli with lot's of middleware layer for data manipulation.