This is the COMBINE study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945872/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945872/ Thus, the results of th

This is the COMBINE study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945872/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945872/ Thus, the results of the COMBINE study demonstrated that a pharmacotherapy, like naltrexone, when given with medical counseling that emphasizes taking medications as prescribed, can yield clinically significant outcomes (reduced drinking/increased abstinence) that are either as compelling, and under some conditions, more compelling than those observed with specialty behavioral therapy. One important implication of the COMBINE results is that naltrexone with MM can be delivered in healthcare settings where traditional specialty treatment is unavailable.