3 ms·
Expression of CD34 and CD117 (aka stem cell growth factor receptor) and blast morphology are pretty definitive, no? Sox2, Oct3/4 and Nanog are good too, but usi
by killjoywashere 8y ago
Expression of CD34 and CD117 (aka stem cell growth factor receptor) and blast morphology are pretty definitive, no? Sox2, Oct3/4 and Nanog are good too, but using transcription factors for cell sorting isn't going to get you very far...
- j7ake 8y agoI think The most unequivocal way to establish you’ve got stem cells is a transplantation experiment on irradiated mice. If you can replenish the cell types of interest after the transplantation experiment, it is convincing that you’ve got a stem fell.