4 ms·

So back to good old aspirin? Acetaminophen slowly kills your liver and Ibuprofen messes with testosterone production.

• tejasmanohar 8y ago
  https://news.ycombinator.com/item?id=18787422 https://news.ycombinator.com/item?id=18787422
• tchaffee 8y ago
  Aspirin kills people too. Usually from stomach bleeding. If it's pain you're trying to reduce the only one I know of that has never killed anyone is cannabis.
• Geimfari 8y ago
  Please note that acetaminophen/paracetamol is incredibly safe at normal doses and does not kill your liver. It is only when you attempt to overdose (or if you have severely limited liver function) that you run out of the liver enzymes that break it down, causing liver damage.
  • sodosopa 8y ago
    At normal doses, Acetaminophen can trigger Stevens-Johnson Syndrome and toxic epidermal necrolysis. You're lucky if you wind up with rashes as opposed to skin falling off.
    • naasking 8y ago
      > At normal doses, Acetaminophen can trigger Stevens-Johnson Syndrome Probably not: https://www.ncbi.nlm.nih.gov/m/pubmed/28963996/ https://www.ncbi.nlm.nih.gov/m/pubmed/28963996/
      • sodosopa 8y ago
        In my case, it does.
        • naasking 8y ago
          So you took acetaminophen in a controlled setting and definitively established a causation? Or was it uncontrolled and could have been caused by any number of uncontrolled variables? Because a definitive causation is publication worthy.