3 ms·
What Defines a Stem Cell?
- killjoywashere 8y agoExpression of CD34 and CD117 (aka stem cell growth factor receptor) and blast morphology are pretty definitive, no? Sox2, Oct3/4 and Nanog are good too, but using transcription factors for cell sorting isn't going to get you very far...
- j7ake 8y agoI think The most unequivocal way to establish you’ve got stem cells is a transplantation experiment on irradiated mice. If you can replenish the cell types of interest after the transplantation experiment, it is convincing that you’ve got a stem fell.